•  From Linate airport to Milan Central railway: bus line "Starfly" at arrivals floor.
Check the time tables.
•  From Milan Central station to Como Nord Lago station(Como downtown): local train.
Check the time tables.
•  From Como downtown to Conference Hotel, you can:

 By car:

•  Take the A51 towards "Venice" (Venezia);
•  passing close to "Sesto San Giovanni" exit towards "Tangenziale Nord";
•  take the A52;
•  take the A4/E64 towards "Como";
•  take the A8 towards "Como";
•  take the A9/E35;
•  Exit at "Como Monte Olimpino" and follow the directions to "Cernobbio" and the "Grand Hotel di Como" (map)
For more details click here or here.